Full publication list

(|| - equal contribution, * - corresponding author(s))

2025

§C. Han, Z. Zhao, H. Gao, J. Deng, Q. Wang, Y. Wang, L. Liu, L. Xu, S. Jiang, X. Zhan,K. Chen, R. Yan, W. Li, W. Huang, K. Xu*, L.Xiang*. “Super-Resolution Diffusivity Mapping Reveals Spatial Correlations Between Lateral Mobility and Structural Heterogeneities on Cellular Membranes”.bioRxiv. 2025.04.01.646704.

§J. Liu, Y. He, R. Yan, J. Yan,R. Wang, Z. Zhang, J. Xia, I. Kireev, K. Xu,K. Chen*. “Excitation Spectral Phasor Microscopy (ExSPM) unveils spatiotemporal heterogeneities in polarity of intracellular lipid droplets”.bioRxiv. 2025.04.03.647137.

§Z. Zhang,Y. He,J. Yan, J. Liu, R. Wang, J. Fan,K. Chen*. “Modulated Excitation Spectral Microscopy: Superior Unmixing and Multiplexed Imaging with Minimal Excitation Wavelengths”.ACS Photonics. 2025.[Virtual special issue“Rising Stars in Photonics”]

§J. Xia, Y. He, Z. Zhang, J. Yan, R. Wang, M. Tang, J. Chen, J. Fan,K. Chen*. “High-throughput, unbiased single-molecule displacement mapping with deep learning reveals spatiotemporal heterogeneities in intracellular diffusivity”.ACS Photonics. 12, 2746, 2025.bioRxiv. 2025.02. 15.638418.[Virtual special issue“Rising Stars in Photonics”]

§H. Zhang, Y. Hu, X. Pu, S. Zhang, Y. He,K. Chen,Z. Liu*. “LED-based multicolor extended resolution transmission fluorescence microscopy”.Journal of Biomedical Optics. 30, 046501, 2025.

2024

§J. Yan^||, Y. He^||,K. Chen*. “Excitation spectral microscopy for highly multiplexed intracellular imaging via quasi-blind unmixing”.ACS Photonics. 11, 3454, 2024. [Virtual special issue“Rising Stars in Photonics”]

2023

§Fanfan Zhai, Li Hao, Xiaomin Chen, Ting Jiang, Qianhong Guo, Liping Xie, Ying Ma, Xiaobo Du, Zhiqin Zheng,Kun Chen*, Jun FAN*.“Single-molecule tracking of PprI in D. radiodurans without interference of autoblinking”.Frontiers in Microbiology, 14, 1256711, 2023.

§L. Xiang, R. Yan,K. Chen, W. Li, K. Xu*. “Single-molecule displacement mapping unveils sign-asymmetric protein charge effects on intraorganellar diffusion”.Nano Letters, 23, 1711, 2023;bioRxiv,2023.01.26.525611.

2022

§K. Chen*, W. Li, K. Xu*. “Super-multiplexing excitation spectral microscopy with multiple fluorescence bands”.Biomed.Opt. Express. 13, 6048, 2022.

§Y. Zhang^||, M. Lu^||, T. Wu,K. Chen, Y. Feng, W. Wang, Y. Li, H. Wei*. “Delay-Spectral Focusing Dual-Comb Coherent Raman Spectroscopy for Rapid Detection in High-Wavenumber Region”.ACS Photonics. 9, 1385, 2022.[Cover story]

§R. Yan,K. Chen, and K. Xu*. “SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport.”Developmental Cell. 57, 512, 2022.

§A. Choi, H. Park,K. Chen, R. Yan, W. Li and K. Xu*. “Displacement statistics of unhindered single molecules show no enhanced diffusion in enzymatic reactions.”J. Am. Chem. Soc.144, 4839, 2022.

§K. Chen, R. Yan, L. Xiang, K. Xu*, "Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing,"Proc. SPIE PC11971, High-Speed Biomedical Imaging and Spectroscopy VII, PC119710A, 2022.

2021

§K. Chen, R. Yan, L. Xiang, K, Xu. “Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing”.Light: Science & Applications.10, 2021.

Accompanying reports about this work:

Bioengineer, “Excitation spectral microscopy”

Phys Org.“Integrate multi-target imaging and quantitative biosensing”

§L. Xiang^||,K. Chen^||, K. Xu*. “Single molecules are your quanta: A bottom-up approach toward multidimensional super-resolution microscopy”.ACS Nano. 15, 12483, 2021.

2020

§L, Xiang^||,K. Chen^||, R. Yan, W. Li, K, Xu. “Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity”.Nature Methods, 17, 524, 2020.

§R. Yan,K. Chen, and K. Xu. “Probing nanoscale diffusional heterogeneities in cellular membranes through multidimensional single-molecule and super-resolution microscopy.”J. Am. Chem. Soc.142, 18866, 2020.

§T. Wu,K. Chen, H. Wei, Y. Li*. “Repetition frequency modulated fiber laser for coherent anti-Stokes Raman scattering”.Opt. Lett. 45, 407, 2020.

2019

§T. Wu,K. Chen, H. Zhao, W. Zhang, Y. Li, H. Wei*. “Flexible dual-soliton manipulation for coherent anti-Stokes Raman scattering spectroscopy”.Optics Express. 26, 26001, 2019.

2017

§K. Chen, T. Wu, T. Chen, T. Zhou, H. Wei, Y. Li*. “Spectral focusing dual-comb coherent anti- Stokes Raman spectroscopic imaging”.Opt. Lett. 42, 3634, 2017.

§K. Chen, T. Wu, Y. Li, H. Wei*. “Quantitative identification of chemical compounds by dual-soliton based coherent anti-Stokes Raman scattering spectroscopy”.Opt. Commun. 404, 177, 2017.

§H. Yang, H, Wei,K. Chen, Y. Li*, S. Zhang. “Simply-integrated dual-comb spectrometer via tunable repetition rates and avoiding selfreferencing”.Optics Express25, 8063, 2017.

§K. Chen*, T. Wu, T. Chen, H. Wei, Y. Li. “Dual-comb Spectral focusing Coherent anti-Stokes Raman spectroscopy”. CLEO: Science and Innovations. Optical Society of America, SW1M. 4, 2017.

2016

§K. Chen, T. Wu, H. Wei, Y. Li*. “Dual-soliton Stokes based background-free CARS spectroscopy and microscopy”.Opt. Lett.41, 2628, 2016.

§K. Chen, T. Wu, T. Zhou, H. Wei, Y. Li*. “Cascaded dual-soliton pulse Stokes for broadband Coherent Anti-Stokes Raman Spectroscopy”.IEEE Photonics Journal. 8, 1, 2016.

§K. Chen, T. Wu, H. Wei, T. Zhou, Y. Li*. “Quantitative chemical imaging with background-free multiplex coherent anti-Stokes Raman scattering by dual-soliton Stokes pulses”.Biomed.Opt. Express. 10, 3927, 2016.

§T. Zhou,K. Chen, H. Wei, Y. Li*. “Improved method for rapid shape recovery of large specular surfaces based on phase measuring deflectometry”.Applied optics55, 2760, 2016.

§T. Zhou,K. Chen, H. Wei, Y. Li*. “Improved system calibration for specular surface measurement by using reflections from a plane mirror”.Applied optics55, 7018, 2016.

§F. Meng,K. Chen, T. Zhou, T. Wu, H. Wei, Y. Li*. “Point-specific self-calibration for improved characterization of thickness distribution”.Optical Engineering55, 084102, 2016.

§H. Yang, H, Wei, H, Zhang,K. Chen, Y. Li, V. O. Smolski, K. L. Vodopyanov*. “Performance estimation of dual-comb spectroscopy in different frequency-control schemes”.Applied optics55, 6321, 2016.

§K. Chen*, T. Wu, H. Wei, Y. Li. “Background-free coherent anti-stokes Raman spectroscopy by all-fiber-generated dual-soliton as Stokes pulse”. CLEO: Science and Innovations. Optical Society of America, SF1O. 3, 2016.

§T. Zhou,K. Chen, H. Wei, Y. Li*. “3D shape reconstruction of specular surfaces by using phase measuring deflectometry”. OTA, SPIE, 2016.

2015

§K. Chen*, T. Wu, H. Wei*, X. Wu, Y. Li. “High spectral specificity of local chemical components characterization with multichannel shift-excitation Raman spectroscopy”.Sci. Rep.5, 13952, 2015 (*Corresponding author).

§K. Chen, H. Wei*, H. Zhang, T. Wu, Y. Li. “A Raman peak recognition method based automated fluorescence subtraction algorithm for retrieval of Raman spectra of highly fluorescent samples”.Ana. Methods, 7, 2770, 2015.

§F. Meng, Y. Li*, X. Wu,K. Chen, H. Wei, X. Wang. “Improved full-field rotating analyzer ellipsometry method for ultrathin film characterization”.Optical Engineering54, 084108, 2015.

2014

§K. Chen*, H. Zhang, H, Wei, Y. Li. “Improved Savitzky–Golay-method-based fluorescence subtraction algorithm for rapid recovery of Raman spectra”.Applied optics53, 5559, 2014.

2013

§K. Chen, Y. Liang*, Y. Zhang. “Study on reflection of human skin with liquid paraffin as the penetration enhancer by spectroscopy”.Journal of Biomed. Opt.18, 105001, 2013.

§K. Chen, Y. Liang*, W. Zhu, X. Sun, T. Wang. “Simulation of temperature distribution in skin under laser irradiation with different wavelengths”.Optik125, 1676, 2013.